Velcade (Velcade) powder for injection 3.5 mg vial №1

Velcade (Velcade) powder for injection 3.5 mg vial №1

Description of the pharmacological action

Bortezomib is a reversible inhibitor himotripsinopodobne activity of the 26S proteasome of mammalian cells.

This proteasome is a large protein complex that breaks down proteins conjugated with ubiquitin. The ubiquitin-proteasomal path plays a key role in the regulation of intracellular concentrations of certain proteins and thus maintains intracellular homeostasis. Inhibition of proteasome activity prevents this selective proteolysis, which can affect a cascade of reactions of signal transmission in the cell. Violation of the mechanism of maintaining homeostasis may result in cell death.

In vivo bortezomib caused a slowdown in many experimental models of human tumors, including multiple myeloma.

Indications for use

- multiple myeloma in combination therapy (1 therapy line);

- multiple myeloma patients who previously received at least 1 line of therapy (therapy 2);

- mantle-cell lymphoma in patients who previously received at least 1 line of therapy

Release form

Lyophilisate for preparation of solution for intravenous infusion 3.5 mg; vial (bottle) 10 ml, packing contour cell 1, a stack of cardboard 1;

Delivery in Ukraine New Mail.

Payment upon receipt or

to PrivatBank card.

Possible delivery to Russia, Moldova and Belarus.

Bring to order any medication from countries

Of the European Union, India, Turkey, Russia and Belarus.

Tel: 0675621331 (Viber); 0999875213 -

call, write - order!

Check out our features!